Dr. Wells’ research is focused on improving health and performance under extreme conditions. He studies the impact of muscle, lung, heart and metabolism diseases on exercise tolerance and uses that information to help develop new ways of treating disease using exercise and nutrition. He also studies new ways of testing and training elite athletes to help improve performance in competition.


Click here for more information on the Human Physiology Research Unit at the University of Toronto.

Peer Reviewed Scientific Journal Articles

Caterini JE, Elzibak AH, Michel EJ, McCrindle BW, Redington AN, Thompson S, Noseworthy MD, Wells GD. Characterizing blood oxygen level-dependent (BOLD) response following in-magnet quadriceps exercise. MAGMA. 2014 Sep 24. [Epub ahead of print]

Russell C, Papadopoulos E, Mezil Y, Wells GD, Plyley MJ, Greenway M, Klentrou P. Acute versus chronic supplementation of sodium citrate on 200 m performance in adolescent swimmers. J Int Soc Sports Nutr. 2014.

White GE, Rhind SG, Wells GD. The effect of various cold-water immersion protocols on exercise-induced inflammatory response and functional recovery from high-intensity sprint exercise. Eur J Appl Physiol. 2014

West SL, Gassas A, Schechter-Finkelstein T, Egeler RM, Nathan PC, Wells GD. Exercise Intolerance and the Impact of Physical Activity in Children Treated With Hematopoietic Stem Cell Transplantation. Pediatr Exerc Sci. 2014 Apr 10.

Banks L, Wells GD, McCrindle BW. Cardiac energy metabolism is positively associated with skeletal muscle energy metabolism in physically active adolescents and young adults. Appl Physiol Nutr Metab. 2014 Mar;39(3):363-8.

Quesnele JJ, Triano JJ, Noseworthy MD, Wells GDChanges in Vertebral Artery Blood Flow Following Various Head Positions and Cervical Spine Manipulation. J Manipulative Physiol Ther. 2013 Nov 15.  

Schneiderman JE, Wilkes DL, Atenafu EG, Nguyen T, Wells GD, Alarie N, Tullis E, Lands LC, Coates AL, Corey M, Ratjen F. Longitudinal Relationship between Physical Activity and Lung Health in Patients with Cystic Fibrosis. Eur Respir J. 2013 Oct 31.

Wells GD, Wilkes DL, Schneiderman JE, Thompson S, Coates AL, Ratjen F. Physiological correlates of pulmonary function in children with cystic fibrosis. Pediatr Pulmonol. 2013 Oct 25.

White G, Wells GD. Cold-Water Immersion & other forms of Cryotherapy: Physiological changes, potential mechanisms, and efficacy for recovery from high intensity exercise. Extreme Physiology and Medicine. 

Quesnelle J, Laframboise M, Wong J, Kim P, Wells GD. The Effects of Beta Alanine Supplementation on Performance. International Journal of Sport Nutrition & Exercise Metabolism.

Shinke R, Kerry R. McGannon, Wells GD. Expanding Understandings of Acculturation in Elite Sport: A Thematic Analysis of Immigrant Athletes and Coaches. Journal of Sport Sciences.

Bessa A, Oliveira V, De Agostini GG, Oliveira R, Oliveira A, White G, Wells G, Teixeira D, Espindola. Exercise intensity and recovery: Biomarkers of injury, inflammation and oxidative stress. Journal of Strength and Conditioning Research.

Quesnelle J, Triano J, Wells GD. Changes in Vertebral Blood Flow following Various Head Positions and Manipulation. Journal of Manual and Physical Therapy.

Lewis EJ, Fraser SJ, Thomas SG and Wells GD. Changes in hydration status of elite Olympic class sailors in different climates and the effects of different fluid replacement beverages. J Int Soc Sports Nutr. 2013 Feb 21;10(1):11. 

Wells GD, O’Gorman CS, Rayner T, Caterini J, Thompson S, Bradley T, Hamilton J. Skeletal Muscle Abnormalities in Girls and Adolescents with Turner Syndrome. Journal of Clinical Endocrinology and Metabolism.

O’Gorman CS, Syme C, Lang J, Bradley T, Wells G, Hamilton J. An Evaluation of Early Cardiometabolic Risk Factors in Children and Adolescents with Turner Syndrome. Clin Endocrinol (Oxf). 2012 Oct 29. 

Jean-St-Michel E, Manlhiot C, Li J, Tropak M, Michelsen MM, Schmidt MR, McCrindle BW, Wells GD and Redington AN. Remote preconditioning improves maximal performance in highly trained athletes. Med Sci Sports Exerc. 2011 Jul;43(7):1280-6. 

Vescovi JD, Falenchuk O and Wells GD. Blood lactate concentration and clearance in elite swimmers during competition. Int J Sports Physiol Perform. 2011 Mar;6(1):106-17. 

Wells GD, Wilkes DL, Schneiderman JE, Rayner T, Elmi M, Selvadurai H, Dell SD, Noseworthy MD, Ratjen F, Tein I and Coates AL. Skeletal muscle metabolism in cystic fibrosis and primary ciliary dyskinesia. Pediatr Res. 2011 Jan;69(1):40-5. 

Balaban DY, Regan R, Mardimae A, Slessarev M, Han JS, Wells GD, Duffin J, Iscoe S, Fisher JA and Preiss D. A simple and portable breathing circuit designed for ventilatory muscle endurance training (VMET). Respir Med. 2009 Dec;103(12):1822-7. Epub 2009 Aug 12. 

Wilkes DL, Schneiderman JE, Nguyen T, Heale L, Moola F, Ratjen F, Coates AL and Wells GD. Exercise and physical activity in children with cystic fibrosis. Paediatr Respir Rev. 2009 Sep;10(3):105-9. Epub 2009 Jul 21. 

Wells GD, Selvadurai H and Tein I. Bioenergetic provision of energy for muscular activity. Paediatr Respir Rev. 2009 Sep;10(3):83-90. Epub 2009 Jul 17. 

Wells GD and Norris SR. Assessment of physiological capacities of elite athletes & respiratory limitations to exercise performance. Paediatr Respir Rev. 2009 Sep;10(3):91-8. Epub 2009 Jul 17. 

Wells GD, Elmi M and Thomas S. Physiological correlates of golf performance. J Strength Cond Res. 2009 May;23(3):741-50. 

Wells GD, Heale L, Schneiderman JE, Wilkes DL, Atenafu E, Coates AL and Ratjen F. Assessment of body composition in pediatric patients with cystic fibrosis. Pediatr Pulmonol. 2008 Oct;43(10):1025-32. 

Ito S, Mardimae A, Han J, Duffin J, Fedorko L, Minkovich L, Katznelson R, Meineri M, Mrenovich A, Wells G, Kessler C, Fisher J. Non-invasive prospective targeting of arterial PCO2 in subjects at rest. Journal of Physiology. 2008 Aug 1;586(Pt 15):3675-82. Epub 2008 Jun 19. 

Wells GD, Wilkes DL, Schneiderman-Walker J, Elmi M, Tullis E, Lands LC, Ratjen F and Coates AL. Reliability and validity of the habitual activity estimation scale (HAES) in patients with cystic fibrosis. Pediatr Pulmonol. 2008 Apr;43(4):345-53. 

Wells GD, Noseworthy MD, Hamilton J, Tarnopolski M and Tein I. Skeletal muscle metabolic dysfunction in obesity and metabolic syndrome. Can J Neurol Sci. 2008 Mar;35(1):31-40. 

Wells GD, Duffin J. Frequency of movements and respiratory control in exercise. Respiratory Physiology & Neurobiology. 2008;161:221–222. 

Wells GD, Diep T and Duffin J. The ventilatory response to sine wave variation in exercise loads and limb movement frequency. Respir Physiol Neurobiol. 2007 Aug 15;158(1):45-50. Epub 2007 Mar 19. 

Wells GD, Schneiderman-Walker J, Plyley M. Normal physiological characteristics of elite swimmers. Pediatric Exercise Science. 2006;18(1): 30-52.

Wells GD, Plyley M, Thomas S, Goodman L and Duffin J. Effects of concurrent inspiratory and expiratory muscle training on respiratory and exercise performance in competitive swimmers. Eur J Appl Physiol. 2005 Aug;94(5-6):527-40. Epub 2005 Jun 8.